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“Nicotine is a potent chemical that changes our brain.” It’s hard to get kids to quit Levy said that “nearly all” adolescents in her program have some experience with e-cigarettes, but “what’s new is that now, we’re seeing patients in the substance use program whose only substance is nicotine.” Health experts worry that getting hooked on nicotine early in life may be a gateway to cigarette smoking and other drugs, and there are few tried-and-true resources out there for teens